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Home Narrowband UV-B Phototherapy in Combination With Low-Dose Acitretin in Patients With Moderate to Severe Psoriasis
Christopher B. Yelverton, MD, MBA;
Brad A. Yentzer, MD;
Adele Clark, PA-C;
Daniel J. Pearce, MD;
Rajesh Balkrishnan, PhD;
Fabian T. Camacho, MS;
Ann Boles, RN, CCRC;
Alan B. Fleischer Jr, MD;
Steven R. Feldman, MD, PhD
Arch Dermatol. 2008;144(9):1224-1225.
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Acitretin plus UV-B phototherapy is a highly effective and relatively safe treatment for psoriasis, limited by the inconvenience and cost of office-based treatment.1 Home phototherapy offers greater convenience, but the safety and efficacy of its use outside the physician's office has not been well studied.2 The purpose of this study is to provide a preliminary assessment of home-based narrowband UV-B phototherapy plus low-dose acitretin for moderate to severe psoriasis.
Methods
After institutional review board approval, 27 adult subjects were recruited. All subjects had moderate to severe plaque-type psoriasis (Psoriasis Area Severity Index [PASI]  12) and no child-bearing potential or contraindications for acitretin or phototherapy. A 4-week washout was required for any systemic psoriasis therapy, . . . [Full Text of this Article]
Results
Comment
AUTHOR INFORMATION
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Home versus outpatient ultraviolet B phototherapy for mild to severe psoriasis: pragmatic multicentre randomised controlled non-inferiority trial (PLUTO study)
Koek et al.
BMJ 2009;338:b1542-b1542.
ABSTRACT
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