 |
|
COMMENTS AND OPINIONS
Does Isotretinoin Increase the Risk of Depression?—Reply
Laurent Azoulay, PhD;
Anick Bérard, PhD
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
In reply
We would like to thank Bigby1 for his commentary in this issue of the Archives on our article.2 Bigby's main concerns surround our strict case definition that may have underestimated the number of patients diagnosed with depression. We agree with Bigby that the underestimate likely occurred, but strict criteria were necessary to ascertain that we had real cases of depression. Defining cases by depression diagnostic codes alone is a questionable practice, given the unknown validity of these codes in the Régie de l'Assurance Maladie du Québec or any other administrative database. Similarly, using the presence of antidepressant prescriptions alone to define cases of depression would have led to the inclusion of noncases because antidepressants are used increasingly for indications other than depression. Thus, requiring that cases have either a diagnosis or hospitalization for depression and presence of an antidepressant prescription resolved these . . . [Full Text of this Article]
AUTHOR INFORMATION
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLE
Does Isotretinoin Increase the Risk of Depression?
Michael Bigby
Arch Dermatol. 2008;144(9):1197-1199.
EXTRACT
| FULL TEXT
RELATED LETTERS
Anatomic Transitions and the Histopathologic Features of Melanocytic Nevi
Toshiaki Saida, Shigeo Kawachi, and Hiroshi Koga
Arch Dermatol. 2008;144(9):1232-1233.
EXTRACT
| FULL TEXT
Anatomic Transitions and the Histopathologic Features of Melanocytic Nevi—Reply
Ashfaq A. Marghoob and Ralph P. Braun
Arch Dermatol. 2008;144(9):1233-1234.
EXTRACT
| FULL TEXT
|
