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Arch Dermatol. 2009;145(1):77-82.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Syringotropic mycosis fungoides (MF).

MICROSCOPIC FINDINGS

Histopathologic examination of the biopsy specimens revealed a slightly acanthotic epidermis, with reticular fibroplasia of the papillary dermis. Intermediate-size lymphocytes with atypia were seen focally along the dermoepidermal junction. The eccrine coils were densely infiltrated with intermediate-size lymphocytes. Immunohistochemical analysis showed a CD4:CD8 ratio of greater than 10:1, and T-cell receptor gene rearrangement studies showed a positive T-cell clone. The diagnosis of syringotropic MF was made.

DISCUSSION

Mycosis fungoides has a wide clinopathologic spectrum ranging from the classic patch-plaque MF to rare forms such as syringotropic MF.¹ Syringolymphoid hyperplasia with alopecia, now recognized to be a premalignant form of syringotropic MF, was first described by Sarkany² in 1969. When the cases of syringolymphoid hyperplasia with alopecia and syringotropic MF described in the literature are counted, the present case brings the total to 18 (13 men and 5 women).³

Because so few cases have been reported, it is difficult to characterize the . . . [Full Text of this Article]

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Arch Dermatol. 2009;145(1):77-82.
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