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Richard W. Hempstead, MD; Nancy L. Hempstead, BS; Leon M. Edelstein, MD

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Report of a Case

A 35-year-old white man complained of a 15-year history of genital herpes simplex and a 5-year history of a generalized herpes eruption manifesting as a pruritic truncal eruption and sweaty palms. The truncal eruption and palmar hyperhidrosis began concurrently 3 months after he sustained a severe "whiplash" injury to the cervical spine from an automobile crash. Neurologic examination was extensive, and all findings were negative. Clinical diagnoses of spinal cord contusion and generalized herpes simplex were rendered by his neurologist. Long-term suppressive acyclovir therapy was ineffective.

While the findings from a neurologic examination were normal, physical examination revealed a truncal eruption comprising numerous 3- to 5-mm faintly tan to red finely scaled papules (Figure 1). Spontaneous palmar sweating occurred with the typical moist, glistening appearance of hyperhidrosis. Six leaflet shave biopsy specimens were taken from the . . . [Full Text of this Article]

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