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Jason H. Neustadter, MD; Frank Samarin, MD; Kacie R. Carlson, PA-C; Michael Girardi, MD

Arch Dermatol. 2009;145(2):127-130.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Morphea, or localized scleroderma, can at times constitute a severely disabling and aggressive disease with no single therapy proven to be curative or the standard of care. Herein, we report the case of a patient with severe disabling generalized deep morphea who showed a marked clinical response to treatment with extracorporeal photochemotherapy (ECP).

REPORT OF CASE

Ten years ago, a 49-year-old white patient presented with a reticulated erythema and induration of her abdominal skin. Over the next 5 years, the erythema and induration progressed to include the skin over her lower extremities, chest, back, and upper extremities. With the onset of new lesions, she frequently experienced pruritus and tenderness at the areas of involvement. She also noted decreased ranges of motion in her shoulders. After a 2-year period without progression, she again developed worsening of her symptoms with progression . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT

AUTHOR INFORMATION

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

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