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COMMENTS AND OPINIONS
Oral Contraceptive and D-Dimer Level
Weekitt Kittisupamongkol, MD
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I read with interest the article by Dompmartin and colleagues.1 A number of participants in the study were women of reproductive age. I was wondering if an important factor elevating D-dimer level was considered: the oral contraceptive pill, a widely prescribed drug, could contribute to such an event.2-3 Failure to be aware of this would lead to an incorrect incidence of high D-dimer levels.
AUTHOR INFORMATION
Correspondence: Dr Kittisupamongkol, Hua Chiew Hospital, 665 Bumrungmuang Rd, Bangkok 10100, Thailand (weekitti@gmail.com).
Financial Disclosure: None reported.
1. Dompmartin A, Acher A, Thibon P; et al. Association of localized intravascular coagulopathy with venous malformations. Arch Dermatol. 2008;144(7):873-877.
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2. Kluft C, Meijer P, LaGuardia KD, Fisher AC. Comparison of a transdermal contraceptive patch vs. oral contraceptives on hemostasis variables. Contraception. 2008;77(2):77-83.
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3. Johnson JV, Lowell J, Badger GJ, Rosing J, Tchaikovski S, Cushman M. Effects of oral and transdermal hormonal contraception on vascular risk markers: a randomized controlled trial. Obstet Gynecol. 2008;111(2, pt 1):278-284.
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Arch Dermatol. 2009;145(2):210.
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