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  Vol. 145 No. 2, February 2009 TABLE OF CONTENTS
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VIGNETTES
In Vivo Reflectance Confocal Microscopy for Cutaneous Metastasis of Bladder Adenocarcinoma

Anna Sgambato, MD; Rosana Bortoli Buffon, MD; Carlo Cota, MD; Antonio Matroianni, MD; Marco Ardigò, MD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Cutaneous metastases from bladder carcinoma occur in less than 1% of patients with this malignant neoplasm and may represent the initial sign of a widespread disease.1 They typically appear as multiple or single well-circumscribed nodules, generally located at a single site, most frequently on the abdomen.1

Histologically, cutaneous bladder carcinoma metastases involve predominantly the dermis, with occasional extension into the subcutaneous tissue. Metastases often show growth of atypical epithelial cells among collagen bundles with a disordered pattern of mixed single narrow strands and large clusters of cells.1

In vivo reflectance confocal microscopy (RCM) is a high-resolution imaging optical tool that allows noninvasive evaluation of skin lesions. It has been already used to evaluate skin tumors and provide high-resolution imaging comparable to histologic analysis.2-4

Report of a Case

A 72-year-old woman presented with a 7-year a history of bladder . . . [Full Text of this Article]


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