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Lichen Planopilaris: Retrospective Study and Stepwise Therapeutic Approach
Lori A. Spencer, MD, PhD;
Elena Balestreire Hawryluk, PhD;
Joseph C. English III, MD
Arch Dermatol. 2009;145(3):333-334.
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Lichen planopilaris (LPP) is a primary lymphocytic scarring alopecia that causes inflammation, erythema, pruritus, dysesthesia, and alopecia that can be treatment resistant. After approval from the institutional review board, we performed a retrospective case analysis of alopecia due to LPP to assess possible therapeutic effectiveness.
Methods
All medical charts with International Classification of Diseases, Ninth Revision (ICD-9) diagnoses of alopecia (2004-2007) were analyzed: 674 cases were nonscarring (81%), and 159 were scarring alopecia (19%). Based on clinicopathologic correlation, LPP was diagnosed in 45 cases (28% scarring alopecia, 5% overall), and all patients were diagnosed by the same observer (J.C.E.). According to the criteria of the North American Hair Research Society,1 histologic evidence of lymphocytic scarring inflammation includes lupus erythematosus (LE), classic pseudopelade, central centrifugal cicatricial alopecia, alopecia mucinosa, keratosis follicularis spinulosa decalvans, and LPP.1
Lichen planopilaris and . . . [Full Text of this Article] Results
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