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Neuropathy and Gait Disturbances in Patients With Venous Disease: A Pilot Study
Meggan R. Newland, MD;
Asha R. Patel, BS;
Luz Prieto, MD;
Andrew J. M. Boulton, MD;
Miriam Pacheco, PhD;
Robert S. Kirsner, MD, PhD
Arch Dermatol. 2009;145(4):485-486.
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We studied less well-investigated components of the calf muscle pump failure associated with venous disease, including muscle, nerve, movement, and gait abnormalities.1 We investigated sensory neuropathy and ambulatory foot pressures in patients with chronic venous insufficiency (CVI) to further elucidate the pathogenesis and mechanisms of venous ulceration.
Methods
After institutional review board approval and informed consent, 10 patients with active noninfected venous ulcers or a history of such ulcers (CEAP [Clinical-Etiologic-Anatomic-Pathophysiologic]1 clinical classification 5 or 6) were recruited. No recruited patient had a history of neuropathy or predisposing conditions for neuropathy. Ten age-, sex-, and weight-matched control patients without diabetes or venous disease were also recruited from the same population. All patients had good arterial circulation and walked without assistance. A medical history was obtained and foot, . . . [Full Text of this Article]
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Dermatologic Comorbidities of Diabetes Mellitus and Related Issues
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Arch Dermatol 2009;145:467-469.
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