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VIGNETTES
HAIR-AN Syndrome in a Male Adolescent With Concomitant Vitiligo
Zhu Shen, MD, PhD;
Fei Hao, MD, PhD;
Ping Wei, MD, PhD
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HAIR-AN syndrome is an unusual multisystem disorder that consists of hyperandrogenism, insulin resistance, and acanthosis nigricans. Specific skin disorders often appear in association with hyposecretion or hypersecretion from the endocrine glands. Knowledge of skin alterations is valuable not only for dermatologists but also for other physicians because a clinical diagnosis of the underlying disease is often possible based on these alterations.1 Herein, we report an unusual skin presentation of HAIR-AN syndrome with concomitant vitiligo in a 16-year-old male adolescent.
Report of a Case
Our patient was obese at presentation (height, 181 cm; weight, 85 kg). Cutaneous velvety thickening with intensification of skin markings in the body folds and on the dorsal aspect of skin overlying the joints (Figure 1) had developed in his early childhood. In the 2 years before presentation, the hyperpigmentation was replaced by progressive vitiligo on the . . . [Full Text of this Article]
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