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  Vol. 145 No. 4, April 2009 TABLE OF CONTENTS
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VIGNETTES
Remission of Extensive Merkel Cell Carcinoma After Electrochemotherapy

Pietro Curatolo, MD; Monica Mancini, MD; Rita Clerico, MD; Arianna Ruggiero, MD; Pasquale Frascione, MD; Pierangelo Di Marco, MD; Mirko Frasca, MD; Stefano Calvieri, MD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Report of a Case

An 83-year-old white man was referred with multiple nodules on the scalp that had appeared 3 months earlier. The nodules were growing rapidly.

He had painless, erythematous, dome-shaped nodules on the scalp. The nodules ranged from 4 x 4 to 10 x 15 mm in diameter (Figure 1). An incisional biopsy specimen revealed small and round cells disposed in a trabecular pattern. Immunohistochemical analysis revealed strong positivity for cytokeratin 20 and neurofilament. On the basis of the histopathologic and immunohistochemical features, Merkel cell carcinoma (MCC) was diagnosed.


 
Figure appears in full text version.
Figure 1. Before treatment, numerous erythematosus dome-shaped nodules are present on the scalp.


A total-body computed tomographic scan demonstrated atypical mediastinal lymph nodes. Surgery and radiotherapy were excluded owing to the extent of the scalp nodules. . . . [Full Text of this Article]


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