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Megan M. Moore, MD; Seth J. Orlow, MD, PhD; Hideko Kamino, MD; Nadia Wang, MD; Julie V. Schaffer, MD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Cole disease is an autosomal dominant genodermatosis characterized by guttate hypopigmentation and palmoplantar keratoses. Initially described in the Archives in 1976,¹ an additional affected family has subsequently been identified.² We herein describe a child with Cole disease, drawing attention to findings that distinguish it from other genodermatoses that feature pigmentary anomalies and punctate keratoderma.

Report of a Case

A healthy 2-year-old boy presented with congenital guttate hypopigmentation on the extremities and asymptomatic papules on the soles that had first appeared at age 3 months. Blisters were observed on the soles at birth, but they had resolved and had not recurred. There was no family history of similar skin lesions.

Examination revealed irregularly shaped, 2- to 10-mm hypopigmented macules on the extremities (Figure 1A and B) and scattered 2- to 8-mm pink-yellowish keratotic papules . . . [Full Text of this Article]

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