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  Vol. 145 No. 4, April 2009 TABLE OF CONTENTS
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 •Infectious Diseases, Other
 •Dermatologic Disorders
 •Liver Transplantation
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VIGNETTES
Immediate Diagnosis of Cryptococcus Fungal Infection Using Touch Preparation Analysis

Nisha C. Patel, MD; Agnieszka Kupiec-Banasikowska, MD; Catharine Lisa Kauffman, MD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We report the diagnosis of Cryptococcus infection by rapid touch preparation analysis (hereinafter, "touch prep") of a skin punch biopsy specimen in a patient undergoing liver transplantation. The diagnosis was subsequently confirmed by histologic findings.

Report of a Case

A 52-year-old man presented with the acute onset of multiple red, tender skin nodules, ranging in size from 2 to 3 cm in diameter, on the posterior aspect of his left arm and right leg. He had a history of end-stage liver disease secondary to hemachromatosis and had undergone orthotopic liver transplantation 4 weeks earlier. Three punch biopsy specimens were obtained from nodules on both arms and the right thigh for routine histologic evaluation and for tissue culture.

Rapid touch prep of a punch biopsy specimen was performed using the Quik Dip procedure (Mercedes Medical, Sarasota, Florida), a histologic staining process, used generally for . . . [Full Text of this Article]


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