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Arch Dermatol. 2009;145(5):589-594.

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Diagnosis: Dermatofibrosarcoma protuberans (DFSP), pigmented variant (Bednar tumor).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histopathologic evaluation revealed a plaquelike spindle-cell proliferation in the dermis and superficial subcutis. Under immunostaining, the tumor cells were strongly and diffusely CD34 positive. A few scattered melanin-containing spindle cells were S-100 protein and melan-A positive. The lesion extended to the side and focally to the deep margins. It was treated via Mohs micrographic surgery. There has been no recurrence to date.

DISCUSSION

Bednar tumors are melanin-containing variants of DFSP first described in 1957 by Bednar¹ as storiform neurofibromas.² Bednar tumors account for 1% to 5% of all DFSP and generally occur on the trunk or proximal extremities.^2-3 Clinically, they usually present as a multinodular, firm, pigmented neoplasm. The surface may appear atrophic or sclerotic.^{2, 4} Bednar tumors may occur in any race but tend to be more common in blacks, with an annual incidence that is approximately 7.5 times higher than that of whites.^3-5 Incidence in male and female patients is . . . [Full Text of this Article]

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Arch Dermatol. 2009;145(5):589-594.
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