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  Vol. 145 No. 5, May 2009 TABLE OF CONTENTS
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VIGNETTES
Remote Hemorrhagic Bullae Occurring in a Patient Treated With Subcutaneous Heparin

Urvi Pajvani Gonzales, MD; Glynis A. Scott, MD; Alice J. Briones, MD; Alice P. Pentland, MD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Hemorrhagic bullae often have underlying infectious causes. However, recent reports have suggested that they may also occur at sites distant from subcutaneous heparin injections,1-2 which have been linked to a variety of other skin manifestations including urticaria, erythema, calcinosis cutis, skin necrosis often secondary to vasculitis, and heparin-induced thrombocytopenia.3-4

Report of a Case

An 88-year-old man with a history of coronary artery disease and hypertension but no history of skin disease reported an asymptomatic eruption of "blood blisters" bilaterally on his lower extremities. The lesions continued to increase in size and number. He had been hospitalized 2 weeks prior to the development of these lesions for treatment of new-onset atrial fibrillation with diltiazem, amiodarone, warfarin, and enoxaparin (low-molecular-weight subcutaneous heparin).

Results of laboratory studies showed a low hemoglobin concentration of 9.5 g/dL (normal range, 14.0-17.5 g/dL), an elevated . . . [Full Text of this Article]


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