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Yi-Ming Fan, MD; Wen-Ming Huang; Wen Li; Guo-Xue Zhang, MM

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Nigrospora is rarely an opportunistic pathogen in humans. To our knowledge, there have been 4 reports on Nigrospora-induced human eye and skin infections in the literature.^1-3 However, none of these cases included definite clinicopathologic evidence or species identification. Herein, we report the first case to our knowledge of Nigrospora sphaerica–induced onychomycosis in humans.

Report of a Case

A 21-year-old man presented with an increasing discoloration of the right first toenail in September 2006. On examination, the whole dorsal surface of the nail plate of the right first toenail was found to be eroded in a powdery, turbid, white patch, and the lateral nail plates showed a brownish discoloration, without subungual hyperkeratosis and onycholysis (Figure 1A). The nail plates of the right second and third toenails were also studded with a few well-circumscribed white patches, but other toenails and toe webs . . . [Full Text of this Article]

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