 |
|
Annular Patches and Plaques on the Scrotum and Buttocks—Diagnosis
Arch Dermatol. 2009;145(6):715-720.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
Diagnosis: Genital porokeratosis.
MICROSCOPIC, LABORATORY FINDINGS, AND CLINICAL COURSE
The histopathologic specimen demonstrated acanthosis, hyperkeratosis, and mild papillomatosis of the epidermis. A parakeratotic column (cornoid lamella) was noted within the stratum corneum, overlying invagination of the epidermis. The granular layer was absent beneath the column, and focal dyskeratosis was evident. The results of all laboratory investigations, including a complete blood cell count, comprehensive metabolic panels, urinalysis, and tests for human immunodeficiency virus, rapid plasma reagin, and herpes simplex virus, were negative.
Clinical and microscopic findings were consistent with a diagnosis of genital porokeratosis, a rare and underreported variant of porokeratosis. Our patient was treated with topical fluorouracil applied twice daily to individual lesions for approximately 8 weeks. This therapy resulted in a partial but temporary clearance of some lesions.
DISCUSSION
Genital porokeratosis is a rare variant of porokeratosis.1-4 Classic porokeratosis of Mibelli was first described by Mibelli and Respighi in 1893. It may be caused by a hyperproliferative mutant clonal . . . [Full Text of this Article]
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLE
Annular Patches and Plaques on the Scrotum and Buttocks—Quiz Case
Lawrence A. Schiffman, Richard Berry, Marvin Watsky, and Ed Heilman
Arch Dermatol. 2009;145(6):715-720.
EXTRACT
| FULL TEXT
|
