 |
|
Mucous Membrane Ulcers in an Immunocompromised Patient—Diagnosis
Arch Dermatol. 2009;145(8):931-936.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
Diagnosis: Cutaneous cytomegalovirus infection (CMV).
MICROSCOPIC FINDINGS
The biopsy specimen showed an acute inflammatory infiltrate (Figure 3). Thorough examination of the endothelial cells demonstrated cytopathic changes and sparse cytoplasmic inclusions, suggesting infection by CMV, which was definitively confirmed by the results of immunoperoxidase staining (Figure 3).
Figure appears in full text version.
|
|
|
|
|
DISCUSSION
Cytomegalovirus is an opportunistic virus that develops in the immunocompromised host. Viral dissemination leads to multiple organ system involvement, with the most important clinical manifestations consisting of pneumonitis, gastrointestinal disease, and retinitis. Cutaneous manifestations are variable and rare, and diagnosis is often delayed. The various clinical presentations that have been reported include ulcers, vesicles, purpuric macules, verrucous lesions, prurigo nodularis–like lesions, erythematous and crusted papules, and digital infarcts.1 However, most of the cases have involved ulcers that were localized mainly on the genital area.
Although CMV usually represents a late manifestation of systemic infection, heralding a fatal course in HIV-positive patients, this is not always . . . [Full Text of this Article]
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLE
Mucous Membrane Ulcers in an Immunocompromised Patient—Quiz Case
Lorena Leal, José Manuel Carrascosa, Aram Boada, and Carlos Ferrándiz
Arch Dermatol. 2009;145(8):931-936.
EXTRACT
| FULL TEXT
|
