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The Relationship Between Lichen Planus and Hepatitis C Clarified
Michael Bigby, MD
Arch Dermatol. 2009;145(9):1048-1050.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Looking at the literature about the association of lichen planus (LP) and hepatitis C virus (HCV) infection brings to mind the parable about blind men examining different parts of an elephant and coming to different conclusions about its appearance. Using meta-analysis of well-selected case-control studies, Shengyuan et al1 provide a complete picture. From their analysis of the data, they conclude that the association exists in some regions (eg, East and Southeast Asia, South America, the Middle East, and Europe) but not in others (eg, North America, South Asia, and Africa).
The point estimate of the summary odds ratio (OR) of the prevalence of HCV exposure in patients with LP and controls was 5.4 (95% confidence interval [CI], 3.5 to 8.3). The positive association was statistically significant and statistically homogeneous among studies from East and Southeast Asia and South America. The positive association was statistically significant and statistically . . . [Full Text of this Article]
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Hepatitis C Virus and Lichen Planus: A Reciprocal Association Determined by a Meta-analysis
Liu Shengyuan, Yao Songpo, Wei Wen, Tian Wenjing, Zhang Haitao, and Wang Binyou
Arch Dermatol. 2009;145(9):1040-1047.
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