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Optical Biopsy at the Bedside
John Strasswimmer, MD, PhD
Arch Dermatol. 2010;146(8):909-910. doi:10.1001/archdermatol.2010.192
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Skin biopsy is essential for the diagnosis of many cutaneous conditions. Beyond the cost and technical considerations, it is an invasive, painful, and scarring procedure. These factors lead dermatologists to be selective about what and when we biopsy, resulting in potential delay and misdiagnosis. Biopsy also is subject to sampling error; because it changes the tissue permanently, it is not amenable to longitudinal evaluation. Because specimen processing creates a delay, some treatment options are limited. Hence, there is a need to develop new noninvasive methods to permit immediate microscopic visualization of tissues in vivo or ex vivo.
One might consider several of the following goals in noninvasive imaging: to make a diagnosis, to measure physiologic variables, to enhance the triage of patients who require biopsy, or to direct the biopsy procedure to sample the most significant portion of a lesion. As noninvasive treatments of cutaneous neoplasms . . . [Full Text of this Article]
AUTHOR INFORMATION
Author Affiliation: Mohs Surgery Institute, Dermatology Associates, Delray Beach, Florida.
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