Figure 2. Deep penetrating nevus. A, Well-demarcated, symmetrical, wedge-shaped lesion with the apex in the subcutaneous fat (hematoxylin-eosin, original magnification x20). B, The lesion consists of melanocytes with oval monomorphous nuclei and abundant pale cytoplasm containing dusty particles of melanin. There are nests of melanocytes at the dermoepidermal junction (hematoxylin-eosin, original magnification x100). C, In some areas, the melanocytes have large pleomorphic nuclei resembling those seen in the Spitz nevus (hematoxylin-eosin, original magnification x200).