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Preliminary Report: 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure to Humans—Seveso, Italy
Arch Dermatol. 1989;125(3):329-330.
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1. Kimbrough RD, ed. Halogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins and related products. New York: Elsevier/NorthHolland Biomedical Press, 1980:322-48.
2. Cerlesi S, Di Domenico A, Ratti S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) persistence in the Seveso (Milan, Italy) soil. Presented at Dioxin '88, Umea, Sweden, August 21-26, 1988. 3. Mastroiacovo P, Spagnolo A, Marni E, Meazza L, Bertollini R, Segni G. Birth defects in the Seveso area after TCDD contamination. JAMA 1988;259:1668-72.
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4. Mocarelli P, Marocchi A, Brambilla P, Gerthoux P, Young DS, Mantel N. Clinical laboratory manifestations of exposure to dioxin in children: a six-year study of the effects of an environmental disaster near Seveso, Italy. JAMA 1986;256:2687-95.
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5. Caramaschi F, Del Corno G, Favaretti C, Giambelluca SE, Montesarchio E, Fara GM. Chloracne following environmental contamination by TCDD in Seveso, Italy. Int J Epidemiol 1981;10:135-43.
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6. Pocchiari F, Silano V, Zampieri A. Human health effects from accidental release of tetrachlorodibenzo-p-dioxin (TCDD) at Seveso, Italy. Ann NY Acad Sci 1979;320:311-20.
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7. Facchetti S, Fornari A, Montagna M. Distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the tissues of a person exposed to the toxic cloud at Seveso. Forensic Environ Appl 1981;1:1406-44.
8. Patterson DG Jr, Hampton L, Lapeza CR Jr, et al. High-resolution gas chromatographic/ high-resolution mass spectrometric analysis of human serum on a whole-weight and lipid basis for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Anal Chem 1987;59:2000-5.
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9. Patterson DG Jr, Needham LL, Pirkle JL, et al. Correlation between serum and adipose tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in 50 persons from Missouri. Arch Environ Contam Toxicol 1988;17:139-43.
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10. CDC Veterans Health Studies. Serum 2,3,7,8-tetrachlorodibenzo-p-dioxin levels in US Army Vietnam-era veterans. JAMA 1988; 260:1249-54.
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11. CDC. Serum 2,3,7,8-tetrachlorodibenzo-pdioxin levels in Air Force Health Study participants—preliminary report. MMWR 1988;37:309-11.
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12. Fingerhut M, Sweeney M, Patterson D, Marlow D, Hornung R, Halperin W. Levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the serum of U.S. chemical workers exposed to dioxincontaminated products. Presented at Dioxin '88, Umea, Sweden, August 21-26, 1988. 13. Beck H, Eckart K, Mathar W, Ruhl C-S, Wittkowski R. Levels of PCDDs and PCDFs in adipose tissue of occupationally exposed workers. Presented at Dioxin '87, Las Vegas, Nevada, October 4-9, 1987. 14. Pirkle JL, Wolfe WH, Patterson DG Jr, et al. Estimates of the half-life of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Ranch Hand Veterans. J Environ Health Toxicol (in press). * Zone R was originally thought to be a reference zone, but on subsequent detection of TCDD concentrations in soil, Zone S was added. ** Levels of TCDD in serum or adipose tissue of the general population are less than 20 ppt.
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