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Maryann Mikhail, MD; Jeffrey M. Weinberg, MD; Barry L. Smith, MD

Arch Dermatol. 2008;144(4):453-456.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Treatment of von Zumbusch pustular psoriasis is a formidable task, especially when confounded by concomitant human immunodeficiency virus (HIV) infection. To our knowledge, this is the first report of successful use of a biologic agent to treat a patient with both von Zumbusch pustular psoriasis and HIV. Given the propensity of HIV to both trigger and exacerbate psoriasis and the potentially severe complications associated with the acute, von Zumbusch variant, we believe this report provides precedence for dermatologists to consider anti–tumor necrosis factor (anti–TNF-) agents as a part of the armamentarium in the treatment of these patients.

REPORT OF A CASE

A 32-year-old man with a history of HIV, psoriasis, and psoriatic arthritis presented with increased joint pain, widespread pruritic pustules, erythema, and intermittent fever with leukocytosis of 2 weeks’ duration (Figure 1 and Figure 2). The patient had an . . . [Full Text of this Article]

CLINICAL CHALLENGE

SOLUTION

COMMENT

AUTHOR INFORMATION

Department of Dermatology, St Luke’s–Roosevelt Hospital Center and Beth Israel Medical Center, New York, New York