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Response of Keratosis Lichenoides Chronica to Efalizumab Therapy
Carlos Muñoz-Santos, MD;
Mireia Yébenes, MD;
Jorge Romaní, MD;
Jesús Luelmo, MD
Arch Dermatol. 2009;145(8):867-869.
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REPORT OF A CASE
A 19-year-old man presented with a 5-year history of a widespread cutaneous eruption. His previous treatment consisted of topical corticosteroids and keratolytics, topical vitamin D derivatives, UV-A phototherapy, oral methotrexate, and oral cyclosporine, without significant improvement. Physical examination revealed bilateral, symmetrical, intensely erythematous lichenoid hyperkeratotic papules forming a linear striated pattern on the antecubital and flexural surfaces of the forearms (Figure 1), popliteal areas, lateral aspect of the trunk, back, periumbilical region, and dorsum of the hands and feet. Erythematous and desquamative papules affected the central facial area, with a seborrheic dermatitislike appearance. Bilateral conjunctival hyperemia was present (Figure 2).
Figure appears in full text version.
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Figure 1. Keratosis lichenoides chronica with tiny keratotic papules that tend to be arranged in a striaelike pattern in the antecubital fold.
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Figure appears in full text version.
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Figure 2. Bilateral conjunctival involvement. Note the seborrheic dermatitislike papules on the . . . [Full Text of this Article]
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THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
AUTHOR INFORMATION
Hospital de Sabadell, Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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