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SULFONES
Gerald Bernstein, MD
5420 Barnes Ave NW Seattle 98107
Arch Dermatol. 1970;102(6):694.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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To the Editor.—
In their review of drug reactions to the sulfones, Millikan and Harrell commented that they were not aware of fatalities from agranulocytosis induced by sulfones.1
A recent report from Vietnam,2 where Dapsone was used as daily prophylaxis against falciparum malaria, cited 16 cases of Dapsone-induced agranulocytosis of which eight patients died. As it was estimated that well over 100,000 troops were taking the Dapsone daily, the incidence of fatalities from agranulocytosis was, of course, very low. Nonetheless, as a result of severe side effects from Dapsone, it is no longer being used routinely for falciparum malaria prophylaxis in Vietnam.
. . . [Full Text PDF of this Article]
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