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I. STUDY OF THE SENSIBILITY OF THE SKIN OF RABBITS TO CHEMICAL IRRITANTS UNDER EXPERIMENTALLY INDUCED CONDITIONS

JOSEPH V. KLAUDER, M.D.; HERMAN BROWN, B.S.

Arch Derm Syphilol. 1925;11(3):283-302.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The theories as to the cause of eczema are well known and need not here be reviewed. From clinical observations, it appears that the skin of patients with eczema is in an increased state of sensibility. Weidenfeld,¹ Schultz,² Hammer,³ Bloch⁴ and others haveshown that the uninvolved skin of the majority of patients with eczema reacts to externally applied irritants in a much greater percentage than normal persons.

Few experimental studies, with the exception of those of Luithlen. have been reported in the direction of determining the pathogenesis of an increased sensibility of the skin as well as conditions that decrease such sensibility.

In this work, Luithlen⁵ employed cats and rabbits. Varying dilutions of croton oil were painted on the shaven skin of these animals the resulting reactions being compared to those following similar applications to another skin area of the same animal subsequent to experiments . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Research Institute of Cutaneous Medicine, Philadelphia. Read at the Forty-Seventh Annual Meeting of the American Dermatological Association, Minneapolis, June, 1924.

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