This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Beth Bjerregaard, MD; KNUD Højgaard, MD
Copenhagen

Arch Dermatol. 1976;112(7):1030-1031.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Progressive systemic scleroderma is a generalized disease, but, in contrast with other collagenous diseases, it rarely involves the nervous system. Definite primary involvement has never been reported, to our knowledge. Most previously reported cases have been associated with nonspecific neurological symptoms secondary to hypertension or to uremia caused by sclerodermic involvement of the heart, lungs, or kidneys.¹

We report a case in which subacute combined degeneration following vitamin B₁₂ deficiency caused by sclerodermic involvement of the small intestine could be an explanation for the neurological symptoms in scleroderma.

Report of a Case.

A 69-year-old woman with a history of crural skin changes and fever attacks of ten years' duration was admitted to the hospital in 1966 with a spastic paraparesis. On the lower part of the legs the epidermis was smooth, shiny, and atrophic, the dermis was sclerotic, and muscular atrophy was found. A skin . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?