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Response to Therapy With Cyclophosphamide

Harold J. Brody, MD; Donald J. Pirozzi, MD

Arch Dermatol. 1977;113(11):1598-1599.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Benign mucous membrane pemphigoid, also called cicatricial pemphigoid, is a chronic vesiculobullous disease of the mucosa and skin that results in permanent scarring of the affected areas, often causing blindness. Reports of treatment for this disorder have been scanty and quite variable in presentation. To our knowledge, this is the first case report of an initially recalcitrant patient treated successfully with cyclophosphamide.

Report of a Case

A 49-year-old man was in good health until June 1975 when he noted injection of the right conjunctiva accompanied by photophobia. The diagnosis was staphylococcal keratoconjunctivitis, and he was treated accordingly with antibiotics and topical steroid combinations with minimal response and progression to the left eye in September of 1975. Several months later an . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Dermatology, Emory University School of Medicine, Atlanta.

Footnotes
Presented in part at the Gross and Microscopic Section, American Academy of Dermatology, 1976.

Reprint requests to Department of Medicine (Dermatology), Emory University School of Medicine, Grady Memorial Hospital, Atlanta, GA 30303 (Dr Brody).

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