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Clinical and Serologic Evaluation for Associated Malignant Neoplasms

A. Razzaque Ahmed, MD; T. Ming Chu, PhD; Thomas T. Provost, MD

Arch Dermatol. 1977;113(7):969.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Bullous pemphigoid (BP) has been reported in association with malignant neoplasms of the urinary tract, lung, genitalia, breast, pancreas, gastrointestinal (GI) tract, skin, and lymphoreticular system.¹ The course of BP usually does not parallel the course of the malignant neoplasm. The malignant neoplasm may be evident at the onset of BP or present as an incidental finding at postmortem examination.²

Carcinoembryonic antigen (CEA) levels greater than 2.5 ng/ml have been reported in serum samples from patients with pancreatic, colonic, rectal, gastric, mammary, and cervical malignant neoplasms, and in some leukemias.³ The presence of CEA correlates with a high incidence of proved malignant neoplasms and is an early indicator of clinically unrecognized recurrence.⁴

The purpose of this study was to determine the incidence of a malignant neoplasm in a large number of patients with BP using clinical as well as serologic evaluation.

Subjects and Methods

Thirty-three patients . . . [Full Text PDF of this Article]

Author Affiliations
From the Departments of Dermatology, State University of New York at Buffalo School of Medicine (Drs Ahmed and Provost), and Diagnostic Immunology, Roswell Park Memorial Institute (Dr Chu), Buffalo. Dr Ahmed is now with the University of California at Los Angeles School of Medicine.

Footnotes
Reprint requests to Department of Dermatology, State University of New York at Buffalo School of Medicine, 50 High St, Buffalo, NY 14203 (Dr Provost).

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