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Phaedon Harsoulis, MD; Florence Kanakoudi-Tsakalidis, MD; Athanasios Vyzantiadis, MD; Aristipos Minas, MD; Christos Cassimos, MD
Thessaloniki, Greece

Arch Dermatol. 1978;114(10):1554.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The autoimmune nature of vitiligo, at least for a certain number of patients, seems to be more and more likely. Previous reports of an increased incidence of organspecific autoantibodies in those patients support this concept.^1-4 The theory has been strengthened recently by the detection of a circulating antibody in two patients with vitiligo, alopecia totalis, mucocutaneous candidiasis, and multiple endocrine insufficiencies, using an immunofluorescent complement-fixation test. This antibody was found bound to melanocytes in human skin, nevus cells, and melanoma cells.⁵

We here report our results of a study that aimed to demonstrate the presence of certain organ-specific autoantibodies in patients with vitiligo and the association of this disorder with autoimmune diseases.

Patients and Methods.—

Eighty-five patients (aged 4 to 78 years) with generalized or localized vitiligo were studied during a period of three years. The patients included in this study were selected on the . . . [Full Text PDF of this Article]

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