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Anita Pedvis-Leftick, MD; Marshall N. Cyrlin, MD; Lawrence M. Solomon, MD

Arch Dermatol. 1979;115(10):1253-1254.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Vitiligo is an acquired localized or generalized total loss of pigment secondary to loss of melanocytes. Its cause is unknown. In 1947, El Mofty¹ introduced the use of methoxsalen for the treatment of vitiligo. Parrish et al² described the use of psoralens in combination with high-intensity long ultraviolet wavelengths (UV-A) as an effective treatment for vitiligo. The UV-A-induced cataract formation has been reported in animals,^3,4 but not in humans. The following is a report of cataracts found in a patient who received photochemotherapy for vitiligo.

Report of a Case

In early 1976, progressive depigmentation of both hands developed in a 42-year-old black woman. There had been no contact with phenolic compounds or history of alopecia, cataracts, vitiligo, diabetes, or thyroid disease. The patient had no history of ophthalmologic disease. She did not have an ophthalmologic examination at that time. The hemoglobin level was 11.2 g/dL, with normal . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Dermatology, Abraham Lincoln School, University of Illinois at the Medical Center (Drs Pedvis-Leftick and Solomon), and the Department of Ophthalmology, University of Illinois Eye and Ear Infirmary (Dr Cyrlin), Chicago.

Footnotes
Reprint requests to the Department of Dermatology, Abraham Lincoln School of Medicine, PO Box 6998, Chicago, IL 60680 (Dr Pedvis-Leftick).

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