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  Vol. 115 No. 12, December 1979 TABLE OF CONTENTS
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Hypertrophic Scarring as a Complication of Fluorouracil Therapy

Lee A. Kaplan, MD; Joseph F. Walter, MD; Kenneth D. Macknet, MD

Arch Dermatol. 1979;115(12):1452.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Scarring is an uncommon accompaniment to fluorouracil therapy of superficial erythematous basal cell carcinoma,1 When scarring occurs, it typically appears as mild atrophy.2 We could find no previous reports of hypertrophic scarring complicating fluorouracil therapy of superficial erythematous basal cell carcinoma, and present the following case.

Report of a Case

A 42-year-old man initially came to the Dermatology Clinic, University of California Medical Center, San Diego, in June 1978 with an 18-month history of a skin lesion on the left side of the upper part of the back. There was no history of previous trauma, skin cancer, or arsenic or x-ray exposure. The patient had sporadically treated the lesion with tolnaftate cream without response.

Physical examination revealed a 2.5 x 2.0-cm erythematous, slightly raised plaque with fine scaling in the above site (Fig 1). An examination for fungi using potassium hydroxide was negative.

A tentative diagnosis of nummular . . . [Full Text PDF of this Article]


Author Affiliations

From the Division of Dermatology, University of California, School of Medicine, San Diego.


Footnotes

Reprint requests to the Division of Dermatology, University of California Medical Center, 225 Dickinson St, San Diego, CA 92103 (Dr Kaplan).



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