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Jon K. Stern, MD; John E. Wolf, Jr, MD; Theodore Rosen, MD

Arch Dermatol. 1979;115(4):497.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Focal acantholytic dyskeratosis is an abnormal cutaneous histologic pattern characterized by suprabasilar clefts with corps ronds and/or grains. These changes are caused by dissociation of intercellular bridges and aberrant keratinization. Once thought to be specific for Darier's disease, these histologic changes may be encountered in a variety of skin diseases. We report a case of pityriasis rosea in which prominent acantholytic dyskeratosis was noted in biopsy material.

Report of a Case

The condition of a 39-year-old woman was evaluated by our consultation service for an eruption involving the trunk and upper and lower extremities; the face, palms, soles, and mucous membranes were spared. Individual lesions were succulent, red papules (3 mm to 2 cm) with fine superficial scaling. All lesions were clearly oriented along body folds and lines of cleavage (Fig 1). Mineral oil preparations for scabies and potassium hydroxide mounts for fungi were negative.

Results of all laboratory tests . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Dermatology, Baylor College of Medicine, Houston. Dr Rosen is currently with the Department of Dermatology, University of Texas, Medical School, Houston.

Footnotes
Reprints not available.

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