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John L. Millns, MD; John A. Doyle, MB; Sigfrid A. MULLER, MD
Rochester, Minn

Arch Dermatol. 1980;116(5):515.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Transient acantholytic dermatosis (Grover's disease), first described in 1970,¹ represents a unique condition of middle-aged and elderly persons; it is characterized by pruritic, discrete, erythematous, edematous papules and papulovesicles located predominantly on the trunk. The condition may last weeks to months and may be exacerbated by exposure to sunlight. During the past few years, several variations of this disorder have been reported. Waisman et al² described three patients with a bullous variant of Grover's disease in which the histologic changes were identical to those of pemphigus foliaceus. Simon et al³ noted a patient with persistent acantholytic dermatosis who had a more prolonged course, and Heaphy et al⁴ coined the term "benign papular acantholytic dermatosis" for a similar group of seven patients.

Scattered reports of direct immunofluorescence microscopy in Grover's disease have recorded negative results to date, with one exception.³ In that study, . . . [Full Text PDF of this Article]

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