This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

James J. Nordlund, MD; Aaron B. Lerner, MD
New Haven, Conn

Arch Dermatol. 1980;116(5):517.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.—

We are pleased to note that Dr Paslin agrees with us on a number of important points regarding the association of melanomas and vitiligo, such as: (1) Vitiligo and melanomas occur together and the association seems to portend a good prognosis for most patients, ie, a long interval of time will pass before the melanoma recurs. (2) Melanomas induce an immune response that on occasion can cause regression of a primary or metastatic tumor and also induce vitiligo. The same immune response, which Paslin notes occasionally causes regression of a primary or metastatic tumor and indirectly induces vitiligo, could just as easily delay the reappearance of the metastasis after excision of the primary.

We take exception to several critical points. Paslin originally noted that the parenteral injection of phenolic agents failed to retard the growth of melanomas in mice.¹ Therefore, he concluded that the application of such . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?