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Lawrence E. Cutler, MD; Joel E. Bernstein, MD; Keyoumars Soltani, MD

Arch Dermatol. 1980;116(6):718-719.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although psoriasis has a familial incidence of about 40%^1,2 and there are abundant data indicating that genetic factors are operative in the cause of psoriasis,^3,4 the mode of inheritance remains controversial. Attempts to ascertain the mode of inheritance have focused on studies of

See also editorial p 657.

twins affected with psoriasis.⁵ However, such studies are often biased owing to the tendency to report only concordant twin pairs.⁶ In this article, we report an unusual pedigree of a family with psoriasis that includes dizygotic twins and trizygotic triplets.

Report of a Case

A 19-year-old man was referred to the University of Chicago Hospitals for treatment of a recent exacerbation of his psoriasis. The patient's condition was first diagnosed as psoriasis at the age of 6 years, and he had subsequently experienced several severe exacerbations, one requiring hospitalization. Clinical examination demonstrated well-circumscribed, erythematous plaques covered by a . . . [Full Text PDF of this Article]

Author Affiliations
From the University of Chicago Hospitals and Clinics and the Pritzker School of Medicine.

Footnotes
Reprint requests to 950 E 59th St, Box 409, Chicago, IL 60637 (Dr Soltani).

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