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Jean Paul Ortonne, MD; René Jeune, MD; Joélle Coiffet, MD; Jean Thivolet, MD

Arch Dermatol. 1981;117(7):443-444.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It has been suggested that the gene responsible for Fanconi's anemia predisposes a person to leukemias as well as to solid tumors.^1-2 The latter have been mainly of two types—hepatocellular carcinomas³ and squamous cell carcinomas.⁴ There have been six described patients with Fanconi's anemia in whom squamous cell carcinomas developed^3-7 (Table). The following case report describes the occurrence of multiple squamous cell carcinomas of the vulva in a young woman with Fanconi's anemia.

Report of a Case

A 24-year-old woman had had a diagnosis of Fanconi's anemia made at the age of 9 years. This diagnosis had been based on the following features: a dirty-gray pigmentation of the genital and perigenital regions extending to the inner surface of the thighs, with five cafe-au-lait spots on the trunk and lower limbs; delayed growth, with below normal weight and height; a right ectopic kidney, with a short ureter . . . [Full Text PDF of this Article]

Author Affiliations
From the Clinique Dermatologique, Hôpital Edouard-Herriot, Lyons France.

Footnotes
Reprint requests to Clinique Dermatologique, Hôpital Edouard-Herriot, 69374 Lyons Cedex 2, France (Dr Thivolet).

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