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Small Cell Carcinoma of the Lung With Leser-Trélat Sign
Akira Hattori, MD;
Yoshio Umegae, MD;
Shigeyuki Kataki, MD;
Takashi Nakajima, MD
Arch Dermatol. 1982;118(12):1017-1018.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Leser-Trélat sign, the sudden appearance and rapid increase in size and number of seborrheic keratoses, frequently accompanied by pruritus, is considered to be indicative of an internal malignant tumor. Adenocarcinoma is the type of malignant neoplasm most commonly associated with the Leser-Trélat sign.1 Herein we report the first case, to our knowledge, in which this sign was associated with small cell carcinoma of the lung.
Report of a Case
A 72-year-old man with a three-year history of diffuse eczematous dermatitis was examined at the Maebashi (Japan) Red Cross Hospital in April 1980. His rash, involving the trunk and the extremities, was pruritic and characterized by papules, erythema, and lichenification. It responded to topical administration of 0.05% fluocinonide. In August 1980, however, the patient noticed the sudden appearance of multiple discrete, hyperpigmented, verrucous lesions on his back, shoulders, and chest (Fig 1). These lesions appeared in areas where the eczematous
. . . [Full Text PDF of this Article]
Author Affiliations
From the Departments of Dermatology (Dr Hattori) and Internal Medicine (Drs Umegae and Kataki), Maebashi (Japan) Red Cross Hospital; and the Pathology Division, National Cancer Center Research Institute, Tokyo (Dr Nakajima).
Footnotes
Reprint requests to Department of Dermatology, Maebashi Red Cross Hospital, 3-21-36 Asahi-cho, PC 371 Maebashi-shi, Japan (Dr Hattori).
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