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Erik Andersen, MD; Rud Andresen, MD; Ole J. Clemmensen, MD
Copenhagen

Arch Dermatol. 1982;118(2):74.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

The editorial by Anderson in the February 1981 ARCHIVES (117:67-68) on dialysis treatment of psoriasis certainly sustains the hope for severely disabled patients with psoriasis who do not respond to conventional therapy. Furthermore, it indicates the importance of a humoral factor or factors somehow involved in the pathogenesis of psoriasis. Immunologic factors may also be pathogenetically involved. The recovery of circulating stratum corneum antibodies¹ and epidermal cell nuclear antibodies² and the demonstration of deposits of immunoglobulin and C3 by immunofluorescent microscopy in psoriatic lesions³ corroborate this view.

Dau⁴ reported the remission of concomitant psoriasis in a patient undergoing plasmapheresis for myasthenia gravis. In addition to the removal of low molecular substances, as in dialysis, plasmapheresis would also eliminate proteins with potential immunologic pathogenetic importance.

Consequently, we decided to perform plasmapheresis in a 54-year-old man with recalcitrant psoriasis of eight years' duration. Since 1977, . . . [Full Text PDF of this Article]

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