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Ramon M. Fusaro, MD, PhD; Henry T. Lynch, MD; William J. Kimberling, PhD
Omaha

Arch Dermatol. 1983;119(1):2-3.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Rahbari and Mehregan (Arch Dermatol 1981;117:328-331) cited Reimer et al¹ and Clark et al² as reporting in 1978 the first example of the FAMMM syndrome. The first report of this syndrome, however, was made in 1968 by Lynch and Krush,³ who described two remarkable cases that had together all three of the essential elements of the FAMMM syndrome: (1) multiple moles of varying sizes and shapes that were clinically suspected of being malignant and that histologically showed very active junctional activity; (2) multiple cutaneous malignant melanomas and inordinately long survival in one patient; and (3) pedigrees disclosing a possible association with primary cancers in other organs (pancreas, respiratory tract, breast, sarcoma, and cervix).

These cases were again evaluated during the 1970s, as part of our ongoing study of cancer patients at our institute for Familial Cancer Management and Control, Omaha. In 1977, Frichot and . . . [Full Text PDF of this Article]

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