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Rhonda Rand, MD; Howard P. Baden, MD

Arch Dermatol. 1983;119(1):81-83.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1871, Harvard became the first American university to establish an independent chair of dermatology and James C. White, MD, was the first to occupy it. At that time, dermatology was becoming recognized as a specialty in this country and American dermatology had declared its independence from the European schools.

In 1889, White¹ described a case of keratosis (ichthyosis) follicularis, while, independently, Professor Ferdinand Jean Darier, MD, published a similar case in Paris, which he called "psorospermose folliculaire végétante."² From then on, keratosis follicularis, psorospermose folliculaire végétante, Darier-White disease, or Darier's disease became an accepted entity. The point-by-point, meticulous clinical description of the disorder by White was accurate; however, in this first account, he failed to describe dyskeratotic cells, the histopathologic hallmark of this disorder. He erroneously postulated that the hair follicle was the primary site of involvement. Darier first described the dyskeratotic regions in the epidermis, but . . . [Full Text PDF of this Article]

Author Affiliations
From the Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston.

Footnotes
Reprints not available.

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