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Lawrence E. Levine, MD; Marilyn G. Pearson, MD; Joseph M. Baron, MD; Maria M. Medenica, MD; James Vardiman, MD
Division of the Biological Sciences University of Chicago Pritzker School of Medicine 5841 S Maryland Ave, Box 409 Chicago, IL 60637

Arch Dermatol. 1984;120(10):1282.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Extramedullary hematopoiesis (EH) is a rare but specific cutaneous manifestation of myelofibrosis with myeloid metaplasia (MMM). With the exception of hemorrhagic purpuric eruptions in neonates, EH has only been described in patients with myelofibrosis.^1-5 We report herein a case of EH of the skin that differs histologically from previously described cases.

Report of a Case.—

A 67-year-old woman was seen in the hematology clinic at the University of Chicago in December 1979 for evaluation of anemia and hepatosplenomegaly. A bone core biopsy disclosed changes consistent with a diagnosis of MMM. Subsequent treatment included 100 mg/day of oral oxymetholone and several hospital admissions during which the patient received a packed RBC transfusion.

In October 1981, the patient was seen in the dermatology clinic with a two-month history of asymptomatic papulonodules on the thighs and trunk. Physical examination showed firm, 5-mm erythematous nodules on the medial aspect of . . . [Full Text PDF of this Article]

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