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Alain Taieb, MD; Isabelle Fontan, MD; Jean Maleville, MD
Service de Dermatologie Hôpital des Enfants F-33077 Bordeaux France

Arch Dermatol. 1985;121(11):1380-1381.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

We were very interested in the article by Jawitz et al¹ concerning intravenous acyclovir treatment of eczema herpeticum (EH) in a 9-month-old female infant. To date, we have treated four infants with severe EH (Kaposi's varicelliform eruption²), ranging from 7 to 14 months of age, with the same regimen. Two of our cases have been reported previously^3,4; all four involved primary herpetic infections caused by herpes simplex virus 1. Fever and general symptoms disappeared between 12 and 72 hours after initiation of acyclovir therapy. Herpes simplex virus 1 was found in eroded lesions during the first three to four days of treatment, but no new vesicles were noted. From our experience, we would like to emphasize some points: (1) As soon as EH is suspected on clinical and cytologic grounds, systemic antistaphylococcal antibiotics must be administered in association with acyclovir therapy; one of our . . . [Full Text PDF of this Article]

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