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A New Look at an Old Compound

David C. Gorsulowsky, MD; John J. Voorhees, MD; Charles N. Ellis, MD

Arch Dermatol. 1985;121(12):1509-1511.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Due to the concern regarding potential side effects of potent topical corticosteroids, attention has recently shifted to the development of other therapeutic modalities for psoriasis. Anthralin is one of the compounds proved long ago to be an effective treatment for psoriasis.¹ However, the standard regimen, as described by Ingram,² is both inconvenient and time consuming. Modifications in formulation, mode of application, and frequency of use have once again rekindled interest in the use of anthralin.

A NEW LOOK

In this issue of the ARCHIVES, Schwarz and Gschnait report new methods of using this old medication. Also, the history of short-contact therapy with anthralin is outlined by Schaefer. Schaefer explains the rationale for using short-contact therapy, and then traces its development and modifications during the past six years. He also describes his elaborate work on percutaneous absorption, which led to his initial use of anthralin in short-contact therapy. . . . [Full Text PDF of this Article]

Author Affiliations
Clinical Pharmacology Unit Department of Dermatology University of Michigan Medical School Ann Arbor, MI 48109-0010

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