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  Vol. 122 No. 5, May 1986 TABLE OF CONTENTS
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Nail Dystrophy in Dyskeratosis Congenita and Chronic Graft-vs-Host Disease

Nancy B. Esterly, MD
Division of Dermatology Children's Memorial Hospital 2300 Children's Plaza Chicago, IL 60614

Arch Dermatol. 1986;122(5):506-507.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

In the November 1985 issue of the ARCHIVES, Ling et al1 describe a girl with dyskeratosis congenita (DCG) simulating chronic graft-vs-host disease (GVHD) and aptly compare and contrast the two conditions. It should be noted, however, that contrary to the statement in their Table 2 (features of DCG and chronic GVHD), nail dystrophy may be a manifestation of chronic GVHD.2-6 The similarity of the nail changes in the two conditions can be appreciated in the accompanying photograph. The Figure, top, depicts the nail dystrophy in a 61/2-year-old boy with DCG who has oral and lingual leukokeratosis and erosions, gray-brown reticulated hyperpigmentation of the groin, lower abdomen, and axillary areas, and pancytopenia. The Figure, bottom, demonstrates the nail dystrophy in a 4-year-old boy with acute myelomonocytic leukemia, treated two years previously by bone marrow transplant, who has documented chronic late-stage GVHD. The nail changes developed concurrent with alopecia and . . . [Full Text PDF of this Article]



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