This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Lumpers vs Splitters

Frederick D. Malkinson, MD, DMD

Arch Dermatol. 1987;123(3):333-337.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1930, Brunsting et al¹ first described the clinical entity of pyoderma gangrenosum (PG) with a report of five cases. Four of these patients had associated ulcerative colitis and the fifth had empyema. In PG the primary skin lesions are often sterile pustules, but vesicles, bullae, nodules, or plaques may precede the typical ulcerations; conversely, primary lesions may be absent altogether or ulcers may follow trauma (pathergy), as noted in four of the original five patients.¹ Single or usually multiple ulcerations of variable size rapidly supersede the early lesions and may enlarge slowly or rapidly. Their borders are sharply defined, serpiginous, and often edematous, violaceous, and extensively undermined. The ulcer margins may be studded with pustules or vesicles and are surrounded by an erythematous zone. The ulcer base is purulent, exudative, and covered with debris and granulation tissue. Cribriform scarring is a frequent . . . [Full Text PDF of this Article]

Author Affiliations
Department of Dermatology Rush-Presbyterian-St Luke's Medical Center 1753 W Congress Pkwy Chicago, IL 60612

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?