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Steven R. Cohen, MD; Peter M. Ross, PhD
Division of Dermatology Cornell University Medical College 1300 York Ave New York, NY 10021; Laboratory of Investigative Dermatology Rockefeller University 1230 York Ave New York, NY 10021

Arch Dermatol. 1988;124(1):19-20.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

We have reexamined the thesis that 4,4'-methylenedianiline (MDA) exposure was responsible for yellow staining of the skin among workers at a molded plastics factory.¹ Barr et al² note that metaphenylenediamine (MPD) is also a component of curing agent Z (Shell Oil Co, Houston), to which the workers were exposed. Figure 1 gives curing agent Z components, provided by Shell as potential health hazards at the time of the 1980 study (published in the ARCHIVES in 1985)¹. Shell did not include MPD as a component. Quite the contrary, information provided by Shell Technical Services attributed the probable cause of staining to MDA. In fact, MPD was acknowledged as a component on the Material Safety Data Sheet of curing agent Z only after 1983 (G. Youngblood, personal communication, March 1987).

To determine which chemical(s) actually caused yellow discoloration of skin, we compared staining properties of reagent . . . [Full Text PDF of this Article]

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