This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (11)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

John P. Joyce, MD; Antoinette F. Hood, MD; Margaret M. Weiss, MD
Department of Dermatology Johns Hopkins Hospital 600 N Wolfe St, Blalock 913-F Baltimore, MD 21205

Arch Dermatol. 1988;124(1):27-28.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

Skin reactions to vitamin K have been previously described in the French and British literature.^1-5 There are only two patients with a delayed cutaneous reaction at the site of intramuscular injection of phytonadione described in the American literature.^6,7 We discuss two additional cases of skin reactions to intramuscular vitamin K injections.

Report of Cases.— CASE 1.—

In June 1981, a 36-year-old woman who was receiving long-term warfarin therapy following mitral valve commissurotomy presented with gastrointestinal and vaginal bleeding. She had received two intramuscular injections of vitamin K₁ in her left lateral deltoid area. The injections, which were given one week apart, were in the form of phytonadione, an aqueous colloidal solution of vitamin K₁. Approximately two weeks after the second injection, she developed a pruritic eruption at the injection sites. Oral antihistamines and intralesional corticosteroid injections were administered without significant symptomatic improvement. . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?