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Cassandra E. Venable, MD; Steven A. Gaudio, MD

Arch Dermatol. 1988;124(11):1707-1708.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

REPORT OF A CASE

A 62-year-old woman was well until eight weeks prior to evaluation when she develped, over a 24-hour period, painless edema of the lower lip without any provoking incident (Fig 1). The edema was more pronounced in the morning, with partial resolution later in the day. No palliation was achieved by warm or cold compresses, courses of several antihistamines, or a seven-day course of erythromycin therapy. There was no history of applied irritants, sensitizers, trauma, prolonged light exposure, photosensitivity, or facial paralysis.

Physical examination revealed swelling of the lower lip with moderate fissuring of her tongue and resolving angular cheilitis. There was no regional lymphadenopathy.

A biopsy specimen was obtained from the lower lip (Fig 2).

What is your diagnosis?

DIAGNOSIS:

Cheilitis granulomatosa.

HISTOPATHOLOGIC FINDINGS

A punch biopsy of the lip revealed spongiosis of the partially keratinized squamous mucosa. There was a patchy . . . [Full Text PDF of this Article]

Author Affiliations
Hospital of the University of Pennsylvania, Philadelphia

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