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Nicola Balato, MD; Sabato De Rosa, MD; Fausta Bordone, MD; Fabio Ayala, MD
Department of Dermatology Second School of Medicine University of Naples Via S. Pansini, 5 80131 Naples, Italy

Arch Dermatol. 1989;125(10):1430-1431.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—

In the September 1986 issue of the ARCHIVES, Biren and Barr¹ postulated that topical application of cyclosporine A could be efficacious in the treatment of cutaneous diseases characterized by a T-cell infiltrate. Frances et al² subsequently reported that topically applied cyclosporine A had been effective in the treatment of oral erosive lichen planus.

Report of Cases.—

During the last year, we had the opportunity to study seven patients who were affected with oral erosive lichen planus that was not associated with internal diseases. All of the patients were unresponsive to traditional forms of treatment. Therefore, they were treated by means of topical applications of 10% cyclosporine A in Labrafil (absolute ethyl alcohol, 10%; oleic polyoxylate glycerides, 30%; and a sufficient quantity of olive oil to make) four times a day (100 mg/d) for 2 months, and then two times a day (50 mg/d) for 2 . . . [Full Text PDF of this Article]

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